Studienliteratur zu Immunologischen Erkrankungen

Zuletzt geändert: 24.06.2026 https://kinderkrebsinfo.de/doi/e123842

Studienliteratur Hämophagozytische Lymphohistiozytose (HLH)

Pubmed

  1. Zivkovic K, Bergsten E, Aricó M, Astigarraga I, Ishii E, Ladisch S, Lehmberg K, Minkov M, Nanduri V, Henter JI: Assessment of intrathecal therapy in the treatment of familial haemophagocytic lymphohistiocytosis. British journal of haematology 2026, 208: 705 [PMID: 41243379] ZIV2026
  2. Hägele P, Staus P, Scheible R, Uhlmann A, Heeg M, Klemann C, Maccari ME, Ritterbusch H, Armstrong M, Cutcutache I, Elliott KS, von Bernuth H, Leahy TR, Leyh J, Holzinger D, Lehmberg K, Svec P, Masjosthusmann K, Hambleton S, Jakob M, Sparber-Sauer M, Kager L, Puzik A, Wolkewitz M, Lorenz MR, Schwarz K, Speckmann C, Rensing-Ehl A, Ehl S, ALPID study group: Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study. The Lancet. Haematology 2024, 11:e114-e126 [PMID: 38302222] HAE2024
  3. Böhm S, Wustrau K, Pachlopnik Schmid J, Prader S, Ahlmann M, Yacobovich J, Beier R, Speckmann C, Behnisch W, Ifversen M, Jordan M, Marsh R, Naumann-Bartsch N, Mauz-Körholz C, Hönig M, Schulz A, Malinowska I, Hines M, Nichols KE, Gil-Herrera J, Talano JA, Crooks B, Formankova R, Jorch N, Bakhtiar S, Kühnle I, Streiter M, Nathrath M, Russo A, Dürken M, Lang P, Lindemans C, Henter JI, Lehmberg K, Ehl S: Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation. Blood 2024, 143: 872 [PMID: 37992218] BOE2024
  4. Zoref-Lorenz A, Lehmberg K, Jordan M: Hemophagocytic Lymphohistiocytosis in the Context of Hematological Malignancies and Solid Tumors. Advances in experimental medicine and biology 2024, 1448, 429 [PMID: 39117831] ZOR2024
  5. Dettmer-Monaco V, Weißert K, Ammann S, Monaco G, Lei L, Gräßel L, Rhiel M, Rositzka J, Kaufmann MM, Geiger K, Andrieux G, Lao J, Thoulass G, Schell C, Boerries M, Illert AL, Cornu TI, Ehl S, Aichele P, Cathomen T: Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis. The Journal of allergy and clinical immunology 2023, [PMID: 37595758] DET2023
  6. Toskov V, Ehl S: Autoimmune lymphoproliferative immunodeficiencies (ALPID) in childhood: breakdown of immune homeostasis and immune dysregulation. Molecular and cellular pediatrics 2023, 10: 11 [PMID: 37702894] TOS2023
  7. Magerus A, Rensing-Ehl A, Rao VK, Teachey D, Rieux-Laucat F, Ehl S: Autoimmune-lymphoproliferative immunodeficiencies (ALPID) A proposed approach to redefining ALPS and other lymphoproliferative immune disorders. The Journal of allergy and clinical immunology 2023 Nov 15; [PMID: 37977527] MAG2023
  8. Böhm S, Wustrau K, Pachlopnik Schmid J, Prader S, Ahlman M, Yacobovich J, Beier R, Speckmann C, Behnisch W, Ifversen M, Jordan MB, Marsh RA, Naumann-Bartsch N, Mauz-Koerholz C, Honig M, Schulz AS, Malinowska I, Hines MR, Nichols KE, Gil-Herrera J, Talano JA, Crooks B, Formankova R, Jorch N, Bakhtiar S, Kühnle I, Streiter M, Nathrath M, Russo A, Duerken M, Lang P, Lindemans CA, Henter JI, Lehmberg K, Ehl S: Survival in primary hemophagocytic lymphohistiocytosis 2016-2021: etoposide is better than its reputation. Blood 2023 Nov 22; [PMID: 37992218] BOE2023
  9. Hines MR, von Bahr Greenwood T, Beutel G, Beutel K, Hays JA, Horne A, Janka G, Jordan MB, van Laar JAM, Lachmann G, Lehmberg K, Machowicz R, Miettunen P, La Rosée P, Shakoory B, Zinter MS, Henter JI: Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults. Critical care medicine 2022, 50: 860 [PMID: 34605776] HIN2022
  10. Ehl S, von Bahr Greenwood T, Bergsten E, Fischer A, Henter JI, Hines M, Lehmberg K, Janka G, Moshous D, Nichols KE: Is neutralization of IFN-γ sufficient to control inflammation in HLH? Pediatric blood & cancer 2021, 68:e28886 [PMID: 33405364] EHL2021
  11. Wegehaupt O, Wustrau K, Lehmberg K, Ehl S: Cell Versus Cytokine - Directed Therapies for Hemophagocytic Lymphohistiocytosis (HLH) in Inborn Errors of Immunity. Frontiers in immunology 2020, 11: 808 [PMID: 32457750] WEG2020
  12. Ehl S, Astigarraga I, von Bahr Greenwood T, Hines M, Horne A, Ishii E, Janka G, Jordan MB, La Rosée P, Lehmberg K, Machowicz R, Nichols KE, Sieni E, Wang Z, Henter JI: Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society. The journal of allergy and clinical immunology. In practice 2018, 6: 1508 [PMID: 30201097] EHL2018
  13. Ehl S, Bogdan C, Niehues T, Borchard G, Baumann U, Hecht J, Koch j, Neubert J, Wiese-Pochelt K, Zepp F: Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen.(II) Impfen bei 1. Primären Immundefekterkrankungen und 2. HIV-Infektion. Bundesgesundheitsblatt 2018, 61: 1034 [PMID: 30062550] EHL2018
  14. Lehmberg K, Ehl S: Hämophagozytische Lymphohistiozytose. Pädiatrische Hämatologie und Onkologie, Hrsg: A. Eggert, C. Niemeyer, Springer Verlag 2. Auflage 2018 [ISSN: 978-3-662-43686-8] LEH2018
  15. Ehl S: Etoposide for HLH: the limits of efficacy. Blood 2017, 130: 2692 [PMID: 29269529] EHL2017
  16. Lehmberg K, Nichols KE, Henter JI, Girschikofsky M, Greenwood T, Jordan M, Kumar A, Minkov M, La Rosée P, Weitzman S: Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies. Haematologica 2015, 100: 997 [PMID: 26314082] LEH2015a
  17. Lehmberg K, Sprekels B, Nichols KE, Woessmann W, Müller I, Suttorp M, Bernig T, Beutel K, Bode SF, Kentouche K, Kolb R, Längler A, Minkov M, Schilling FH, Schmid I, Vieth S, Ehl S, Zur Stadt U, Janka GE: Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents. Br J Haematol 2015, 170: 539 [PMID: 25940575] LEH2015
  18. Trottestam H, Berglöf E, Horne A, Onelöv E, Beutel K, Lehmberg K, Sieni E, Silfverberg T, Aricò M, Janka G, Henter JI: Risk factors for early death in children with haemophagocytic lymphohistiocytosis. Acta paediatrica (Oslo, Norway : 1992) 2012, 101: 313 [PMID: 22017632] TRO2012
  19. Pagel J, Beutel K, Lehmberg K, Koch F, Maul-Pavicic A, Rohlfs AK, Al-Jefri A, Beier R, Bomme Ousager L, Ehlert K, Gross-Wieltsch U, Jorch N, Kremens B, Pekrun A, Sparber-Sauer M, Mejstrikova E, Wawer A, Ehl S, zur Stadt U, Janka G: Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5). Blood 2012, 119: 6016 [PMID: 22451424] PAG2012
  20. Janka GE: Familial and acquired hemophagocytic lymphohistiocytosis. Annual review of medicine 2012, 63: 233 [PMID: 22248322] JAN2012
  21. Trottestam H, Horne A, Aricò M, Egeler RM, Filipovich AH, Gadner H, Imashuku S, Ladisch S, Webb D, Janka G, Henter JI, Histiocyte Society: Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol. Blood 2011, 118: 4577 [PMID: 21900192] TRO2011
  22. Janka GE: Hemophagocytic syndromes. Blood reviews 2007, 21: 245 [PMID: 17590250] JAN2007a
  23. Henter JI, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G: HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatric blood & cancer 2007, 48: 124 [PMID: 16937360] HEN2007
  24. Ouachée-Chardin M, Elie C, de Saint Basile G, Le Deist F, Mahlaoui N, Picard C, Neven B, Casanova JL, Tardieu M, Cavazzana-Calvo M, Blanche S, Fischer A: Hematopoietic stem cell transplantation in hemophagocytic lymphohistiocytosis: a single-center report of 48 patients. Pediatrics 2006, 117:e743 [PMID: 16549504] OUA2006
  25. Filipovich AH: Life-threatening hemophagocytic syndromes: current outcomes with hematopoietic stem cell transplantation. Pediatric transplantation 2005, 9 Suppl 7: 87 [PMID: 16305623] FIL2005
  26. Imashuku S, Kuriyama K, Sakai R, Nakao Y, Masuda S, Yasuda N, Kawano F, Yakushijin K, Miyagawa A, Nakao T, Teramura T, Tabata Y, Morimoto A, Hibi S: Treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) in young adults: a report from the HLH study center. Medical and pediatric oncology 2003, 41: 103 [PMID: 12825212] IMA2003
  27. Henter JI, Samuelsson-Horne A, Aricò M, Egeler RM, Elinder G, Filipovich AH, Gadner H, Imashuku S, Komp D, Ladisch S, Webb D, Janka G, Histocyte Society: Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood 2002, 100: 2367 [PMID: 12239144] HEN2002a
  28. Holter W, Ressmann G, Grois N, Lehner M, Parolini O, Gadner H: Normal monocyte-derived dendritic cell function in patients with Langerhans-cell-histiocytosis. Medical and pediatric oncology 2002, 39: 181 [PMID: 12210447] HOL2002
  29. Imashuku S: Clinical features and treatment strategies of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Critical reviews in oncology/hematology 2002, 44: 259 [PMID: 12467966] IMA2002
  30. Imashuku S, Kuriyama K, Teramura T, Ishii E, Kinugawa N, Kato M, Sako M, Hibi S: Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001, 19: 2665 [PMID: 11352958] IMA2001
  31. Dürken M, Finckenstein FG, Janka GE: Bone marrow transplantation in hemophagocytic lymphohistiocytosis. Leukemia & lymphoma 2001, 41(1-2): 89 [PMID: 11342360] DUE2001
  32. Baker KS, DeLaat CA, Steinbuch M, Gross TG, Shapiro RS, Loechelt B, Harris R, Filipovich AH: Successful correction of hemophagocytic lymphohistiocytosis with related or unrelated bone marrow transplantation. Blood 1997, 89: 3857 [PMID: 9160694] BAK1997
  33. Henter J, Arico M, Egeler R, Elinder G, Favara B, Filipovich A, Gadner H, Imashuku S, Janka-Schaub G, Komp D, Ladisch S, Webb D: HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society. Med Pediatr Oncol 1997, 28: 342 [PMID: 9121398] HEN1997
  34. Henter JI, Elinder G, Ost A: Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Seminars in oncology 1991, 18: 29 [PMID: 1992521] HEN1991
  35. Blanche S, Caniglia M, Girault D, Landman J, Griscelli C, Fischer A: Treatment of hemophagocytic lymphohistiocytosis with chemotherapy and bone marrow transplantation: a single-center study of 22 cases. Blood 1991, 78: 51 [PMID: 2070059] BLA1991