Trial literature on germ cell tumours

Literature concerning trials for intracranial and extracranial germ cell tumours

Last modification: 2017/01/05

Intracranial germ cell tumours


  1. Kaatsch P, Häfner C, Calaminus G, Blettner M, Tulla M: Pediatric germ cell tumors from 1987 to 2011: incidence rates, time trends, and survival. Pediatrics 2015, 135:e136 [PMID: 25489016] KAA2015
  2. Calaminus G, Kortmann R, Worch J, Nicholson JC, Alapetite C, Garrè ML, Patte C, Ricardi U, Saran F, Frappaz D: SIOP CNS GCT 96: final report of outcome of a prospective, multinational nonrandomized trial for children and adults with intracranial germinoma, comparing craniospinal irradiation alone with chemotherapy followed by focal primary site irradiation for patients with localized disease. Neuro-oncology 2013, 15: 788 [PMID: 23460321] CAL2013
  3. Göbel U, von Kries R, Teske C, Schneider DT, Beyerlein A, Bernbeck B, Calaminus G: Brain metastases during follow-up of children and adolescents with extracranial malignant germ cell tumors: Risk adapted management decision tree analysis based on data of the MAHO/MAKEI-registry. Pediatric blood & cancer 2012, Epub ahead of print [PMID: 22693072] GOE2012
  4. Göbel U, Schneider DT, Teske C, Schönberger S, Calaminus G: Brain metastases in children and adolescents with extracranial germ cell tumor - data of the MAHO/MAKEI-registry. Klinische Padiatrie 2010, 222: 140 [PMID: 20514616] GOE2010a
  5. Calaminus G: Intrakraniale Keimzelltumoren. Monatsschr Kinderheilkd 2008, 156: 1181–1186 [DOI: 10.1007/s00112-008-1797-5] CAL2008
  6. Schneider DT, Zahn S, Sievers S, Alemazkour K, Reifenberger G, Wiestler OD, Calaminus G, Göbel U, Perlman EJ: Molecular genetic analysis of central nervous system germ cell tumors with comparative genomic hybridization. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006, 19: 864 [PMID: 16607373] SCH2006c
  7. Göbel U, Calaminus G, Schneider DT, Koch S, Teske C, Harms D: The malignant potential of teratomas in infancy and childhood: the MAKEI experiences in non-testicular teratoma and implications for a new protocol. Klinische Padiatrie 2006, 218: 309 [PMID: 17080332] GOE2006b
  8. Calaminus G, Andreussi L, Garré ML, Kortmann RD, Schober R, Göbel U: Secreting germ cell tumors of the central nervous system (CNS). First results of the cooperative German/Italian pilot study (CNS sGCT). Klinische Padiatrie 1997, 209: 222 [PMID: 9293454] CAL1997

Extracranial germ cell tumours


  1. Kaatsch P, Häfner C, Calaminus G, Blettner M, Tulla M: Pediatric germ cell tumors from 1987 to 2011: incidence rates, time trends, and survival. Pediatrics 2015, 135:e136 [PMID: 25489016] KAA2015
  2. Göbel U, Calaminus G, Haas R, Teske C, Schönberger S, Schneider DT, Leuschner I, Harms D: Testicular germ cell tumors in adolescents - results of the protocol MAHO 98 and the identification of good risk patients. Klinische Padiatrie 2014, 226(6-7): 316 [PMID: 25431864] GOE2014
  3. Wessalowski R, Schneider DT, Mils O, Friemann V, Kyrillopoulou O, Schaper J, Matuschek C, Rothe K, Leuschner I, Willers R, Schönberger S, Göbel U, Calaminus G, MAKEI study group: Regional deep hyperthermia for salvage treatment of children and adolescents with refractory or recurrent non-testicular malignant germ-cell tumours: an open-label, non-randomised, single-institution, phase 2 study. The lancet oncology 2013, 14: 843 [PMID: 23823158] WES2013a
  4. Hofmann M, Schlegel PG, Hippert F, Schmidt P, von-Schweinitz D, Leuschner I, Göbel U, Calaminus G, Schneider DT, MAKEI study group: Testicular sex cord stromal tumors: Analysis of patients from the MAKEI study. Pediatric blood & cancer 2013, 60: 1651 [PMID: 23733594] HOF2013
  5. Schönberger S, Okpanyi V, Calaminus G, Heikaus S, Leuschner I, Nicholson JC, Stoecklein NH, Schneider DT, Borkhardt A: EPCAM-A novel molecular target for the treatment of pediatric and adult germ cell tumors. Genes, chromosomes & cancer 2013, 52: 24 [PMID: 22987628] SCH2013
  6. Masqué-Soler N, Szczepanowski M, Leuschner I, Vokuhl C, Haag J, Calaminus G, Klapper W: Absence of BRAF mutation in pediatric and adolescent germ cell tumors indicate biological differences to adult tumors. Pediatric blood & cancer 2012, 59: 732 [PMID: 22147429] MAS2012
  7. Hennes E, Zahn S, Lopes LF, Schönberger S, Leuschner I, Göbel U, Calaminus G, Schneider DT: Molecular genetic analysis of bilateral ovarian germ cell tumors. Klinische Padiatrie 2012, 224: 359 [PMID: 23143763] HEN2012
  8. Calaminus G, Göbel U, Schrum J, Wittkugel O, Westphal M, Timmermann B: Proton beam therapy for loco-regional control of a recurrent mixed malignant germ cell tumor of the skull in a 22-month-old girl. Klinische Padiatrie 2010, 222: 175 [PMID: 20514623] CAL2010
  9. Bernbeck B, Schneider DT, Bernbeck B, Koch S, Teske C, Lentrodt J, Harms D, Göbel U, Calaminus G, MAKEI-Study Group: Germ cell tumors of the head and neck: report from the MAKEI Study Group. Pediatric blood & cancer 2009, 52: 223 [PMID: 18937314] BER2009
  10. Steffens J, Treiyer A, Calaminus G: [Management of pediatric testicular tumors : diagnosis, therapy, and follow-up]. Der Urologe. Ausg. A 2009, 48: 359 [PMID: 19280171] STE2009
  11. Calaminus G, Schneider DT, Weissbach L, Schönberger S, Okpanyi V, Leuschner I, Poremba C, Göbel U: Survival after an antiangiogenetic therapy and surgery in a wide spread growing teratoma originating from a testicular mixed malignant germ cell tumor. Klinische Padiatrie 2009, 221: 136 [PMID: 19437360] CAL2009
  12. Zahn S, Sievers S, Alemazkour K, Orb S, Harms D, Schulz WA, Calaminus G, Göbel U, Schneider DT: Imbalances of chromosome arm 1p in pediatric and adult germ cell tumors are caused by true allelic loss: a combined comparative genomic hybridization and microsatellite analysis. Genes, chromosomes & cancer 2006, 45: 995 [PMID: 16897744] ZAH2006
  13. Biskup W, Calaminus G, Schneider DT, Leuschner I, Göbel U: Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96. Klinische Padiatrie 2006 Nov-Dec; 218: 303 [PMID: 17080331] BIS2006
  14. Calaminus G, Bamberg M, Harms D, Jürgens H, Kortmann RD, Sörensen N, Wiestler OD, Göbel U: AFP/beta-HCG secreting CNS germ cell tumors: long-term outcome with respect to initial symptoms and primary tumor resection. Results of the cooperative trial MAKEI 89. Neuropediatrics 2005, 36: 71 [PMID: 15822019] CAL2005